Introduction
In cleanroom environments, maintaining cleanliness and controlling contamination is critical. Microfiber cleanroom wipes are one of the most effective tools for this purpose. They are widely used in industries such as semiconductors, pharmaceuticals, electronics, aerospace, and biotechnology.
This guide provides a complete overview of how to use microfiber cleanroom wipes correctly. Whether you’re in a Class 10 cleanroom or a general lab, using the wipes properly ensures maximum cleaning efficiency and minimal particle release.

What Are Microfiber Cleanroom Wipes?
Microfiber cleanroom wipes are made of polyester and nylon fibers, tightly woven to capture even the smallest particles. These wipes are:
-
Low-linting
-
Highly absorbent
-
Durable and soft
-
Compatible with a range of disinfectants
They are suitable for ISO Class 3 to Class 7 cleanroom use.
Benefits of Using Microfiber Cleanroom Wipes
- Superior Particle Trapping – Ultra-fine fibers trap dust, microbes, and particles.
- Chemical Compatibility – Can be used with IPA, acetone, and other solvents.
- Streak-Free Cleaning – Ideal for glass, lenses, and polished surfaces.
- Reusable Options Available – Some microfiber wipes can be sterilized and reused.
When to Use Microfiber Cleanroom Wipes
Microfiber wipes are ideal for:
-
Daily cleanroom maintenance
-
Wiping down benches and equipment
-
Cleaning tools and instruments
-
Spill control and liquid absorption
-
Electronics and optical component handling

How to Use Microfiber Cleanroom Wipes Effectively
1. Choose the Right Type of Wipe
Select based on:
-
Cleanroom classification (ISO level)
-
Absorbency needs
-
Surface type (glass, metal, plastic)
-
Sterile or non-sterile requirement
2. Prepare the Area
- Ensure you are in cleanroom attire.
- Use a sticky mat at the entrance.
- Avoid introducing outside contaminants.
3. Use the Proper Folding Method
Fold the wipe in quarters to:
-
Increase cleaning surface area
-
Prevent cross-contamination
-
Maintain wipe integrity
4. Wipe in a Controlled Pattern
-
Use straight overlapping strokes.
-
Start from cleanest to dirtiest area.
-
Discard or refold the wipe after each pass.
5. Dispose or Store Correctly
-
Single-use wipes should be disposed of in a cleanroom trash container.
-
Reusable wipes must be placed in a clean, labeled container for laundering.

Tips for Different Industry Applications
Semiconductor Industry
-
Use wipes to clean wafer surfaces and tools.
-
Combine with cleanroom IPA for deep cleaning.
-
Avoid lint to reduce particle contamination.
Pharmaceutical Industry
-
Use sterile microfiber wipes for GMP compliance.
-
Wipe down clean benches, isolators, and vials.
-
Dispose of after a single use.
Optics and Lens Manufacturing
-
Clean glass surfaces and lenses gently.
-
Use low-linting microfiber wipes only.
-
Ensure no streaks are left behind.
Aerospace and Electronics
-
Clean circuit boards and control panels.
-
Use ESD-safe microfiber wipes.
-
Reduce static and avoid surface damage.

Common Mistakes to Avoid
-
Using the same wipe for multiple areas
-
Not refolding the wipe during cleaning
-
Using incorrect wiping patterns
-
Not following cleanroom protocol
Storage and Handling
- Store wipes in original, sealed packaging.
- Keep in a controlled environment.
- Avoid exposure to moisture, sunlight, and dust.
- Always check expiration dates (for sterile products).
OEM & ODM Microfiber Cleanroom Wipes
If you require customized microfiber cleanroom wipes, choose a supplier offering:
-
Custom sizes and packaging
-
Private label branding
-
Sterile and non-sterile options
-
Material and absorbency customization

Conclusion
Microfiber cleanroom wipes are vital tools for maintaining contamination-free environments. By using the proper techniques for wiping, folding, and disposal, you can maximize their effectiveness. Industries such as semiconductors, biotech, aerospace, and pharmaceuticals benefit greatly from these high-performance cleaning tools.
Looking for high-quality cleanroom wipes?
Contact us for OEM & ODM solutions tailored to your cleanroom needs!